Photodynamic Therapy (PDT) is a non-invasive, in-office treatment that combines a topical photosensitizing agent with a specific wavelength of light to selectively destroy abnormal or precancerous skin cells. It is most commonly used to treat actinic keratoses (AKs)—precancerous lesions caused by sun damage—but is also effective in addressing acne and supporting skin cancer prevention in high-risk individuals.

At our practice, we offer two FDA-approved topical photosensitizers for PDT:

  • Aminolevulinic acid (ALA)
  • Ameluz® (aminolevulinic acid hydrochloride in gel form)

Both agents are absorbed by abnormal cells and become activated upon exposure to a specialized light source, leading to targeted destruction of damaged tissue while preserving the surrounding healthy skin.

Conditions commonly treated with PDT:

  • Actinic keratoses (face, scalp, and other sun-exposed areas)
  • Inflammatory acne
  • Field cancerization for patients with extensive sun damage
  • Adjunctive treatment for non-melanoma skin cancer prevention

Benefits of PDT include:

  • Non-surgical, tissue-preserving approach
  • Minimal downtime and no systemic effects
  • Can treat multiple lesions simultaneously
  • Improves overall skin tone and texture in sun-damaged areas

Following treatment, patients can expect some redness, swelling, or peeling as the skin heals. Strict photoprotection is required for 48 hours post-procedure due to increased sensitivity to light.

If you’ve been diagnosed with actinic keratoses, have a history of chronic sun exposure, or are interested in a non-invasive treatment for acne or cancer prevention, Photodynamic Therapy may be an effective option. We invite you to schedule a consultation to learn more about how PDT can support your skin health.